Mississippi Roast isn’t just another slow-cooked beef recipe—it’s the kind of dish that solves dinner before you even realize you need help. Rich, tangy, melt-in-your-mouth tender, and unbelievably comforting, this Mississippi Roast delivers bold flavor with minimal effort. From busy weeknights to lazy Sunday meals, it’s the answer when you want something deeply satisfying without complicated prep. With simple ingredients and a foolproof slow-cooking method, this version of Mississippi Roast creates juicy, shreddable beef bathed in a savory, pepperoncini-spiked gravy that tastes like it simmered all day—because it did.
Table of Contents
Table of Contents
Why You’ll Love This Recipe
- Set-It-and-Forget-It Comfort Food – Once the roast is in the slow cooker, it does all the work while you get on with your day.
- Simple Ingredients, Big Flavor – Everyday pantry staples come together to create a deeply savory, tangy gravy.
- Ultra-Tender Beef Every Time – Slow cooking breaks down the meat until it practically falls apart.
- Versatile & Crowd-Pleasing – Serve it over noodles, potatoes, rice, or piled high on sandwich rolls.
- Balanced, Not Overpowering – The pepperoncini add gentle heat and brightness without making the dish spicy.
What sets this Mississippi Roast apart is the homemade ranch-style dressing blended directly into the cooking liquid, creating a smoother, richer sauce than packet-based versions—without sacrificing that iconic flavor everyone loves.
Ingredients Needed

For the Roast
- 1 boneless chuck roast or top/bottom round roast (3–4 pounds) – Chuck roast is ideal for maximum tenderness.
- 2 teaspoons kosher salt, plus more to taste – Enhances the natural beef flavor.
- 1½ teaspoons freshly ground black pepper, plus more to taste – Adds warmth and depth.
- ¼ cup all-purpose flour – Helps form a crust and lightly thickens the sauce.
- 3 tablespoons neutral oil (such as canola or vegetable oil) – For browning the meat.
- 4 tablespoons unsalted butter – Adds richness to the final gravy.
For the Signature Flavor
- 8–12 whole pepperoncini – Tangy, mildly spicy peppers that define Mississippi Roast.
For the Creamy Ranch-Style Sauce
- 2 tablespoons mayonnaise – Forms the creamy base of the sauce.
- 2 teaspoons apple cider vinegar – Brightens and balances the richness.
- ½ teaspoon dried dill – Adds classic ranch flavor.
- ¼ teaspoon sweet paprika – Provides subtle warmth and color.
- 1 teaspoon buttermilk (optional) – Loosens the sauce and adds tang.
To Finish
- Chopped fresh parsley – For a fresh, vibrant garnish.
How to Make Mississippi Roast

Step 1: Season and Coat the Roast
Place the roast on a sturdy cutting board and pat it dry with paper towels—this helps the seasoning adhere and improves browning. Rub the salt and black pepper evenly over all sides of the meat. Sprinkle the flour over the roast and gently massage it in, ensuring a thin, even coating. This step creates a flavorful crust and helps thicken the sauce later.
Step 2: Sear for Maximum Flavor
Heat the oil in a large, heavy skillet over high heat until shimmering and just beginning to smoke. Carefully place the roast into the pan. Sear for 4–5 minutes per side, turning until all surfaces are deeply browned. This caramelization builds rich, beefy flavor that carries through the entire dish. Transfer the seared roast to the bowl of a slow cooker.
Step 3: Build the Slow Cooker Base
Place the butter directly on top of the roast, then scatter the pepperoncini around and over the meat. Cover with the slow cooker lid and set the temperature to low. Starting on low ensures the beef cooks gently, resulting in a tender, juicy texture rather than dry or stringy meat.
Step 4: Mix the Creamy Dressing
While the roast begins to warm, prepare the sauce. In a small bowl, whisk together the mayonnaise, apple cider vinegar, dried dill, and paprika until smooth and fully emulsified. If using buttermilk, whisk it in last to slightly thin the mixture. The dressing should be creamy but pourable.
Step 5: Add Sauce and Slow Cook
Remove the slow cooker lid and spoon the dressing evenly over the roast. Replace the lid and allow the Mississippi Roast to cook undisturbed for 6–8 hours, until the meat easily shreds when pulled with two forks. Avoid lifting the lid too often—trapped heat and moisture are key to tender results.
Step 6: Shred and Serve
Once fully cooked, shred the beef directly in the slow cooker, mixing it thoroughly with the rich gravy surrounding it. Taste and adjust seasoning with additional salt and pepper if needed. Finish with a generous sprinkle of chopped parsley before serving.

Serving and Storage Tips
Serving Ideas:
- Spoon Mississippi Roast over buttery egg noodles or creamy mashed potatoes.
- Serve with roasted potatoes or steamed rice for a hearty plate.
- Pile the shredded beef onto toasted sandwich rolls with extra gravy for an unforgettable sandwich.
- Pair with simple sides like green beans, carrots, or a crisp salad to balance the richness.
Storage:
- Store leftovers in an airtight container in the refrigerator for up to 4 days.
- For longer storage, freeze cooled roast and gravy for up to 3 months.
Reheating:
- Reheat gently on the stovetop over low heat, adding a splash of broth if needed.
- Microwave in short intervals, stirring to maintain moisture.
Helpful Notes
- Chuck roast works best due to its marbling, but round roasts can be used for a leaner result.
- Pepperoncini juice can be added (1–2 tablespoons) for extra tang if desired.
- For a thicker gravy, remove the lid during the final 30 minutes of cooking.
- This recipe adapts well to meal prep and tastes even better the next day as flavors deepen.
Conclusion
Mississippi Roast is proof that simple ingredients can create extraordinary results. With its fall-apart tender beef, tangy pepperoncini, and luxuriously rich gravy, this dish checks every box: easy, comforting, versatile, and deeply satisfying. Whether you’re feeding a crowd or just want guaranteed leftovers, this slow-cooked classic never disappoints.
If you try this Mississippi Roast, don’t forget to leave a comment and a ⭐⭐⭐⭐⭐ rating—it helps others discover the recipe too. Share your creation on Pinterest or Facebook and let everyone know how you served it. Did you add your own twist or variation? I’d love to hear about it in the comments below!
Frequently Asked Questions (FAQ)
Can I make Mississippi Roast without a slow cooker?
Yes. You can prepare it in a Dutch oven and cook it in the oven at 300°F (150°C) for about 3½–4 hours, covered, until fork-tender.
Is Mississippi Roast spicy?
No. Pepperoncini are mild and tangy rather than hot. They add flavor without noticeable heat.
How do I make this recipe gluten-free?
Simply replace the all-purpose flour with a gluten-free flour blend or cornstarch for dredging.
Can I freeze Mississippi Roast?
Absolutely. Allow it to cool completely, then freeze in airtight containers for up to three months. Thaw overnight in the refrigerator before reheating.
Why is my gravy too thin or too thick?
If it’s too thin, cook uncovered for 20–30 minutes or stir in a cornstarch slurry. If too thick, add a small amount of broth or water to loosen it.

Mississippi Roast
Ingredients
Method
- Pat the roast dry with paper towels. Season all sides with salt and black pepper, then coat lightly with flour, pressing it into the surface.
- Heat the oil in a large skillet over high heat. Sear the roast for 4–5 minutes per side until deeply browned. Transfer the roast to the slow cooker.
- Place the butter on top of the roast and scatter the pepperoncini around it. Cover and set the slow cooker to low.
- In a small bowl, whisk together mayonnaise, apple cider vinegar, dried dill, paprika, and buttermilk if using, until smooth.
- Spoon the creamy dressing evenly over the roast. Cover and cook on low for 6–8 hours, until the beef is fork-tender.
- Shred the beef directly in the slow cooker and stir it into the gravy. Adjust seasoning if needed and garnish with fresh parsley before serving.